Messanae Universitas Studiorum

Acetoacetilazione della nucleasi di stafilococco aureo. Correlazione tra criteri conformazionali chimico-fisici ed immunologici

Di Bello, Carlo (1974) Acetoacetilazione della nucleasi di stafilococco aureo. Correlazione tra criteri conformazionali chimico-fisici ed immunologici. Accademia Peloritana dei Pericolanti, Classe di Scienze FF. MM. NN., LIV. pp. 7-11.

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Abstract

Staphylococcal nuclease has been modified by reaction with an excess of diketane. Spectroscopic and immunological features of the native protein and of the derivative have been compared. Unlike acetylation or trifluoroacetylation, acetoacetylation of the lysine residues, has been found to produce a marked disorganization in the conformation of the enzyme. The modified enzyme shows a new absorption band, not present in simple model compounds. Removal of blocking groups from the modified enzyme by hydroxylamine is not complete.

Item Type: Article
Subjects: M.U.S. - Miscellanea > Atti Accademia Peloritana > Classe di Scienze Fisiche, Matematiche e Naturali > 1974 (2)
Depositing User: Dr A F
Date Deposited: 30 Oct 2012 11:01
Last Modified: 30 Oct 2012 11:01
URI: http://cab.unime.it/mus/id/eprint/1573

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