Effetti dell'isosorbide dinitrato sulla pressione intraoculare nell'occhio normale e glaucomatoso

Oreto, G. and Tripodi, G. and Manganaro, Antonio and Cacopardi, M. and Castagna, I. (1980) Effetti dell'isosorbide dinitrato sulla pressione intraoculare nell'occhio normale e glaucomatoso. Accademia Peloritana dei Pericolanti Classe scienze medico - biologiche, 68. pp. 373-383.

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Abstract

The effects of the acute sublingual administration of Isosorbide dinitrate upon heart rate, blood pressure and intraocular pressure have been studied in 20 patients affected by open-angle glaucoma and in 20 normal subjects.
The heart rate changed slightly only in the noimal subjects, while the blood pressure diminished promptly in both groups. The intraocular pressure raised briefiy in the normal subjects, while it did not show any change in the glaucomatous ones.
These data suggest that, otherwise it was beiieved in the past, the Isosorbide dinitrate does not cause any harmful effect in patients with open-angle glaucoma.

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