Manfrè, C. (1998) Mastocitosi localizzate infantili. Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche, LXXXVI (1). pp. 79-84.
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Mastocytosis may present during infancy, childhood, or adulthood. The disease is characterized by an increased number of tissue mast cell. The organ sistem most frequently involved is the skin (cutaneous mastocytosis); however, mastocytosis may involve the lymphoreticular (liver, spleen, lymphnodes), gastrointestinal, bone marrow, and skeletal system (systemic mastocytosis).The symptoms are both isolated to the organ system involved and systemic, due to local or genaralized release, respectively, of histamine and other mast cell mediators, i.e., leukotrienes, prostaglandins and platelet-activating factor. Plasma histamine levels may be elevated in pediatric-onset mastocytosis.
Treatment usually involves the use of H1 and H2 antihistamine to control itching and to control the hypersecretion of gastrc acid that may occur.
|Subjects:||M.U.S. - Miscellanea > Atti Accademia Peloritana > Classe di Scienze Medico-Biologiche > 1998|
M.U.S. - Miscellanea > Atti Accademia Peloritana > Classe di Lettere, Filosofia e belle Arti > 1998
|Depositing User:||Dr PP C|
|Date Deposited:||07 Jan 2013 11:03|
|Last Modified:||07 Jan 2013 11:03|
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