Messanae Universitas Studiorum

Modificazioni selettive del glutatione e degli enzimi implicati nel suo metabolismo durante lo sviluppo del sarcoma ascite di Yoshida del ratto

Bottari, C. and Cavallaro, A. and Salmeri, F. M. and Picciurro, D. and Pisani, D. and Fimiani, V. (1996) Modificazioni selettive del glutatione e degli enzimi implicati nel suo metabolismo durante lo sviluppo del sarcoma ascite di Yoshida del ratto. Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche, LXXXIV (1). pp. 141-149.

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    Abstract

    During Yoshida ascites sarcoma growth the decrease in rate of cell proliferation was followed by decrease in protein synthesis, GSH, GSSG, ATP, GSH-S-transferase and $\gamma$-GCS; by increase in GSH-peroxidase; while GSH-reductase and G-6-PD remained unchanged. In relation to growth curve of the tumor, GSH concentration was very high up to day 7 (logaritmic phase), decreased till quantity similar to that of corresponding normal cells up to day 10 (plateau phase) and on day 13 was significantly smaller. Correlation between high concentration of GSH in tumor cells and their survival and proliferation after intraperitoneal implantation is discussed.

    Item Type: Article
    Subjects: M.U.S. - Miscellanea > Atti Accademia Peloritana > Classe di Scienze Fisiche, Matematiche e Naturali > 1996
    M.U.S. - Miscellanea > Atti Accademia Peloritana > Classe di Scienze Medico-Biologiche > 1996
    M.U.S. - Miscellanea > Atti Accademia Peloritana > Classe di Scienze Giuridiche, Economiche e Politiche > 1996
    M.U.S. - Miscellanea > Atti Accademia Peloritana > Classe di Lettere, Filosofia e belle Arti > 1996
    Divisions: UNSPECIFIED
    Depositing User: Dr PP C
    Date Deposited: 04 Apr 2013 10:19
    Last Modified: 04 Apr 2013 10:19
    URI: http://cab.unime.it/mus/id/eprint/3311

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