# Conformation of dermorphin in solution and in the presence of lipids

Cavatorta, P. and Spisni, A. and Morante, S. and Paris, V. and Farruggia , G. and Franzoni, L. and Masotti, L. (1991) Conformation of dermorphin in solution and in the presence of lipids. Accademia Peloritana dei Pericolanti Classe FF.MM.NN., 69. pp. 81-90.

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## Abstract

Dermorphin has been studied in various solvents (DMSO, TFE and $H_2$O) using spectroscopic techniques such as CD and NMR. Potential energy minimization of the peptide structure has been carried out to verify the indications obtained from the spectroscopic data. All the results suggest the existence of a $\beta$-bend involving the central and carboxy-terminal part of the molecule. These findings could give reason of the behavior of the peptide in the presence of lipid moieties, where only a slight interaction is observed.

Item Type: Article M.U.S. - Miscellanea > Atti Accademia Peloritana > Classe di Scienze Fisiche, Matematiche e Naturali > 1991 > Supplemento 1M.U.S. - Miscellanea > Atti Accademia Peloritana > Classe di Scienze Giuridiche, Economiche e Politiche > 1991 > Supplemento 1M.U.S. - Miscellanea > Atti Accademia Peloritana > Classe di Lettere, Filosofia e belle Arti > 1991 > Supplemento 1 Dr M P 01 Oct 2012 09:59 01 Oct 2012 09:59 http://cab.unime.it/mus/id/eprint/812