Peptidil vinil chetoni inibitori irreversibili della rodesaina: ottimizzazione della porzione P3.

IRACI, BENEDETTA (2019) Peptidil vinil chetoni inibitori irreversibili della rodesaina: ottimizzazione della porzione P3. Laurea Magistrale thesis, UNSPECIFIED.

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Abstract

Human African Trypanosomiasis (HAT), well-known as sleeping sickness, is a protozoan disease endemic in more than 30 countries in sub-Saharan Africa, where it continues to be an significant cause of morbidity and mortality, mainly in the rural areas, despite the substantial decrease of new cases reported in the last years.The etiological agents of HAT are two Trypanosoma subspecies: T. brucei gambiense is mainly predominant in central and western Africa, where is the cause of a chronic course disease, whereas T. brucei rhodesiense is widespread in southern and eastern Africa, where is responsible of an acute form of HAT, characterized by a fast onset and a high mortality.

Item Type: Tesi (Laurea Magistrale)
Subjects: Scienze Chimiche
Dipartimento: Dipartimento di Scienze chimiche, biologiche, farmaceutiche ed ambientali
Depositing User: Dott.ssa Santina Francolino
Date Deposited: 10 Jul 2020 06:51
Last Modified: 10 Jul 2020 06:51
URI: http://cab.unime.it/tesi/id/eprint/4630

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