An elderly man with congenital hypogammaglobulinemia and persistent cough

Abstract

We report here the case of a 71 year-old male, former smoker of 60 pack-years, with an history of congenital hypogammaglobulinemia associated to recurrent fever and persistent productive cough, treated with immunoglobulin G (IgG) replacement therapy. On the last 3 years he was followed by our outpatient clinic for chronic respiratory failure (treated with long-term oxygen therapy) secondary to diffuse bilateral bronchiectasis and pulmonary panacinar emphysema. The patient did not follow our influenza and pneumococcal vaccinations recommendations. The patient died after 3 years of follow-up.We report here an unusual case in an adult of diffuse and bilateral bronchiectasis secondary to congenital hypogammaglobulinemi