Hepatitis e virus seroprevalence in farmed animals: a public health risk

Michela Pugliese, Rocky La Maestra, Pietro Paolo Niutta

Abstract


Hepatitis E virus (HEV) is a zoonotic virus typically associated with acute self-limited or fulminant hepatitis in humans. The disease transmitted by oral-fecal route is endemic in many developing countries where sanitation conditions are suboptimal. In industrialized countries, the transmission occurs from animals to humans by the consumption of contaminated water, raw/undercooked animal products or inner organs.The swine is the most important reservoir of HEV zoonotic transmission, but the high seroprevalence of HEV in other animals indicates a theirpotential role in the transmission of disease. Indeed, the high sequence similarity between cattle, sheep, swine, and human populations suggests a complicated interspecies transmission. The aim of this review is to detail the current knowledge of the HEV in farmed animals, focusing on their role in the transmission of HEV.

Keywords


Hepatitis E, farmed animals, foodborne transmission, zoonosis, genotype

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References


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DOI: https://doi.org/10.6092/1828-6550/APMB.108.1.2020.SD2

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