An unusual association in a patient with COVID-19-related ARDS and bilateral pleural effusion

Antonio Cipolla, Antonio Faiello, Giuseppe Ielo, Giorgio Morana, Federica Lo Bello, Alfio Proietto, Carlo Vanchieri, Gaetano Caramori

Abstract


We present the case of a 76-year-old female, previously diagnosed with pulmonary sarcoidosis, that was admitted to our Unit of Pulmonology for acute hypoxemic respiratory failure secondary to COVID-19-related acute respiratory distress syndrome (ARDS) and with bilateral pleural effusions. Despite the therapy the patient’s conditions gradually deteriorated during the hospital stay with progressive hypoxemia and the patient died 36 days after the admission

Keywords


acute respiratory failure, sarcoidosis, pleural effusion, pneumonia

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References

1. Baughman, R.P., Lower, E.E. (2021). COVID-19 infections in sarcoidosis: a prospective single center study of 886 sarcoidosis patients. Sarcoidosis Vasc Diffuse Lung Dis. 38(2), e2021029. doi: 10.36141/svdld.v38i2.11646.

2. Ji, X., Lu, J., Zuo, A., Sun, F., Peng, H., Lu, D. (2022) Pleural involvements in pulmonary sarcoidosis: A case report and review of the literature. Front. Med.(9), 902711. doi: 10.3389/fmed.2022.902711.

3. Chong, W.H., Saha, B.K., Conuel, E., Chopra, A. (2021). The incidence of pleural effusion in COVID-19 pneumonia: State-of-the-art review. Heart Lung. 50(4), 481-490. doi: 10.1016/j.hrtlng.2021.02.015.

4. Rathore, S.S., Hussain, N., Manju, A.H., Wen, Q., Tousif, S., Avendaño-Capriles, C.A., Hernandez-Woodbine, M.J., Rojas, G.A., Vatsavayi, P., Tera, C.R., Ali, M.A., Singh, R., Saleemi, S., Patel, D.M. (2022). Prevalence and clinical outcomes of pleural effusion in COVID-19 patients: A systematic review and meta-analysis. J Med Virol.94(1), 229-239. doi: 10.1002/jmv.27301.

5. Duong, H.T., Bonham, C.A. (2018). Sarcoidosis-associated pulmonary hypertension: pathophysiology, diagnosis and treatment. ClinPulm Med. 25(2),52-60.doi:10.1097/CPM.0000000000000252

6. Mirsaeidi, M., Omar, H.R., Baughman, R., Machado, R., Sweiss, N. (2016). The association between BNP, 6MWD test, DLCO% and pulmonary hypertension in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis.33(4),317-320.

7. Ichinose, A., Otani, H., Oikawa, M., Takase, K., Saito, H., Shimokawa, H., Takahashi, S. (2008). MRI of cardiac sarcoidosis: basal and subepicardial localization of myocardial lesions and their effect on left ventricular function. AJR Am J Roentgenol. 191(3),862-9. doi: 10.2214/AJR.07.3089.

8. Kiko, T., Yoshihisa, A., Kanno, Y., Yokokawa, T., Abe, S., Miyata-Tatsumi, M., Misaka, T., Oikawa, M., Kobayashi, A., Ishida, T., Takeishi, Y. (2018). A Multiple Biomarker Approach in Patients with Cardiac Sarcoidosis. Int Heart J.59(5),996-1001. doi: 10.1536/ihj.17-695.

9. Darlington, P., Gabrielsen, A., Cederlund, K., Kullberg, S., Grunewald, J., Eklund, A., Sörensson P. (2019). Diagnostic approach for cardiac involvement in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 36(1),11-17. doi: 10.36141/svdld.v36i1.7132.

10. Dökümcü, E. (2021). The role of carbohydrate antigen 125 in COVID-19. Med Hypotheses.151:110590. doi: 10.1016/j.mehy.2021.110590.

11. Ros-Lucas, J.A., Pascual-Figal, D.A., Noguera-Velasco, J.A., Hernández-Vicente, Á., Cebreiros-López, I., Arnaldos-Carrillo, M., Martínez-Ardil, I.M., García-Vázquez, E., Aparicio-Vicente, M., Solana-Martínez, E., Ruiz-Martínez, S.Y., Fernández-Mula, L., Andujar-Espinosa, R., Fernández-Suarez, B., Sánchez-Caro, M.D., Peñalver-Mellado, C., Ruiz-López, F.J. (2022). CA 15-3 prognostic biomarker in SARS-CoV-2 pneumonia. Sci Rep.(1):6738. doi: 10.1038/s41598-022-10726-7.

12.Kalluri, M., Judson, M.A. (2007). Sarcoidosis associated with an elevated serum CA 125 level: description of a case and a review of the literature. Am J Med Sci. 334(6):441-3. doi: 10.1097/MAJ.0b013e3180f60bc4.

13. Türk, Y., Shapiro, C., Braunstahl, G.J. (2017). CA 15.3: a marker of disease activity in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 34(1):100-101. doi: 10.36141/svdld.v34i1.4786.

14. Sharma, O.P.(2000). Hypercalcemia in granulomatous disorders: a clinical review. Curr Opin Pulm Med.6(5),442-7. doi: 10.1097/00063198-200009000-00010.

15. Baughman, R.P., Janovcik, J., Ray, M., Sweiss, N., Lower, E.E.(2013). Calcium and vitamin D metabolism in sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 30(2), pp. 113-120




DOI: https://doi.org/10.13129/1828-6550/APMB.111.1.2023.CCS1

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Copyright (c) 2023 Antonio Cipolla, Antonio Faiello, Giuseppe Ielo, Giorgio Morana, Federica Lo Bello, Alfio Proietto, Carlo Vanchieri, Gaetano Caramori

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